Basic Sterilization Concepts

Q:1

The process of sterilization is used for which of the following dosage forms?

a)OSD

b)Parenterals

c)Ophthalmics

d) b&c

The correct Answer Is (d)

Q:2

With Terminal sterilization, we may get assurance of not more than____ non-sterile units out of One Million.

a)One

b)Two

c)Three

d)Four

The correct Answer Is (a)

 

Basic Sterilization

 

Q:3

For Thermal sensitive products which is true regarding sterilization?

a)Can be achieved by high temperature.

b)Can be achieved by low temperature.

c)Can be achieved by low temperature & antimicrobial Agent

d)None Of The Above

The correct  Answer Is (c)

Q:4

All microorganisms have _____ resistance to sterilization.

a)Same

b)Different

c)No Resistance

d)None Of the Above

The correct Answer Is (b)

Q:5

Which of the following is more resistant to the sterilization process?

a)Spores

b)Vegetative Cells

c)Both

The correct Answer Is (a)

Q:6

The Microbial death kinetics is expressed by which of the following?

a)D-Value

b)U-Value

c)T-Value

d)Dt-Value

The correct Answer Is (a)

Q:7

D-Value is the dose used for microbes to decrease their____ population.

a)50%

b)70%

c)90%

d)100%

The correct Answer Is (c)

Q:8

D Value is used for which of the following types of sterilization?

a)Heat

b)Radiation

c)Chemical

d)All Of the Above

The correct Answer Is (d)

Q:9

D Value is usually not used for which of the following types of sterilization?

a)Heat

b)Radiation

c)Chemical

d)Gass

The correct Answer Is (d)

Q:10

The effectiveness of heat sterilization depends on which of the following?

a)Degree Of Heat

b)Exposure Time

c)Moisture Content

d)All Of the Above

The correct Answer Is (d)

Q:11

Dry heat sterilization is used for those substances which are not degraded at which of the following temperatures?

a)Above 121°C

b)Above 130°C

c)Above 140°C

d)Above 160°C

The correct Answer Is (c)

Q:12

Spores & Vegetative forms of microorganisms can be killed at 180°C within?

a)1 Hr

b)1.5 Hrs

c)2.0 Hrs

d)3.0 Hrs

The correct Answer Is (c)

Q:13

Spores & Vegetative forms of microorganisms can be killed at 260°C within?

a)30 Minutes

b)45 Minutes

c)60 Minutes

d)None Of the Above

The correct Answer Is (b)

Q:14

Dry Heat sterilization works on the principle of?

a)Oxidizing Proteins

b)Oxidizing DNA

c)Reduction Of Lipids

d)All Of the Above

The correct Answer Is (a)

Q:15

For the sterilization of powders, which of the following methods of sterilization is used?

a)Dry Heat

b)Moist Heat

c)Filtration

d)All of the above

The correct Answer Is (a)

Q:16

Moist Heat Sterilization Is also known as?

a)Wet Steam

b)Autoclaving

c)Hot Shower

d)All Of the Above

The correct Answer Is (b)

Q:17

Which of the following heat sterilization methods is more effective?

a)Dry Heat

b)Moist Heat

c)Moderate Heat

d)Radiation

The correct Answer Is (b)

Q:18

Moist Heat sterilization works on the principle of?

a)Oxidizing Proteins

b)Coagulation Of Proteins

c)Reduction Of Proteins

d)All Of the Above

The correct Answer Is (b)

Q:19

Usually, Autoclave Works on which of the following parameters?

a)20 Min 15 psig & 121 °C

b)15 Min 20 psig & 121 °C

c)30 Min 15 psig & 121 °C

d)20 Min 15 psig & 131 °C

The correct Answer Is (a)

Q:20

Vitamins & antibiotics in powder form can be sterilized by?

a)Dry Heat

b)Moist Heat

c)Radiation

d)All Of the Above

The correct Answer Is (c)

Q:21

Sterilization using filters works on the principle of?

a)Sieving

b)Straining

c)Sticking

d)All Of the Above

The correct Answer Is (a)

Q:22

Membrane Filters are available in which of the following forms?

a)Discs

b)Pleated Cylinder

c)Cartridge

d)All of the above

The Correct Answer Is (d)

Q:23

Filtration sterilization is used for those products which require?

a)Terminal Sterilization

b)Non-Terminal Sterilization

c)Radiation Sterilization

d)None Of the Above

The correct Answer Is (b)

Q:24

Filtration sterilization is used for which of the following products ?

a)Degraded By heat

b)Degraded By Pressure

c)Degraded By Filters

d)None Of the Above

The correct Answer Is (a)

Q:25

For sterilization of air, which of the following sterilization methods is used?

a)Moist Heat

b)Dry Heat

c)Radiation

d)Filtration

The correct Answer Is (d)

Q:26

Which Of the following gasses are used for gas sterilization?

a)Ethylene Oxide

b)Beta Propiolactone

c)Propylene Oxide

d)All Of the Above

The correct Answer Is (d)

Q:27

Which Of the following gas requires a long sterilization cycle ?

a)Ethylene Oxide

b)Beta Propiolactone

c)Propylene Oxide

d)All Of the Above

The correct Answer Is (c)

Q:28

Which Of the following gas is used in solution form for sterilization of surgical instruments?

a)Ethylene Oxide

b)Glutaraldehyde

c)Propylene Oxide

d)BPL

The Correct Answer Is (b)

Q:29

Which of the following is used for the sterilization of plastic & paperboard?

a)Dry heat

b)Moist Heat

c)Gas Sterilization

d)Filtration

The correct Answer Is (c)

Q:30

Which of the following oxidizing gasses are used for gas sterilization?

a)Hydrogen Peroxide

b)Ozone

c)Peracetic Acid

d)All of above

The correct Answer Is (d)

Q:31

Which of the following is an advanced type of sterilization?

a)Ultrahigh Pressure

b)HILP

c)Gas Plasma

d)All of above

The correct Answer Is (d)

Q:32

Which of the following are used for the evaluation of the sterilization process?

a)Biological Indicator

b)Temperature Monitoring

c)Moisture Penetration

d)All of above

The correct Answer Is (a)

Reference:

Theory & Practice Of Industrial Pharmacy By Lachman.

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