Tablet Weight Variation
Weight variation is tablet compression defect where weight of compressed tablets is not within ranges described by official pharmacopoeias…
Month: January 2021
Methods Of Bidder Addition For Wet Granulation
Binders are the most important excipients used to combine powder particles with each other to form granules in wet granulation.Wet granulation is the most commonly used method of manufacturing granules for tablets and capsules in pharmaceutical industries. To learn complete wet granulation method read following, Description of wet granulation. In wet granulation binder can be … Read more
Meglumine
Meglumine is less common and not a well-known excipient because it is not commonly used in most of pharmaceutical formulations. About 70% of pharmacists working in pharmaceutical industries may not be aware of this excipient but its importance can not be ignored because of those drugs which have poor aqueous solubility.Meglumine is an amino sugar … Read more
Hydroxypropyl Cellulose|HPC
Hydroxypropyl Cellulose is a derivative of cellulose and it is used as an excipient in different pharmaceutical dosage forms.USP 32 NF-27 defines the HPC as a partially substituted derivative of cellulose and it may contain not more than 0.6% Silica or any other anticaking agent. Other Names HPC is also known Functions Of HPC HPC … Read more
Qualification|IQ|DQ|OQ|PQ|URS|FAT|SAT
Qualification is documented evidence that all the equipment, system, facility, or utility are designed, installed, and operated in such a way that complies with GMP requirements and produces products of the desired quality all the time. Qualification is a part of validation and consists of following If we discuss in a detailed manner then some … Read more
Hydroxypropyl Methylcellulose|HPMC
Hydroxypropyl Methylcellulose is a derivative of cellulose and is a semisynthetic excipient used in oral liquid, ophthalmic, nasal, topical, and oral solid dosage form preparations. It is a tasteless, odorless granular, or fibrous powder. Hydroxypropyl Methylcellulose is commonly known as Numbering System Examples 2208 is known as K grade and 2910 is known as E … Read more
Colloidal Silicon Dioxide|Fumed Silica
Colloidal Silicon Dioxide is commonly known as fumed silica.It is a very common and interesting excipient because it has a very small particle size and large surface area. Interesting in the sense that only 10 kg of Colloidal Silicon Dioxide can fill approximately the 40 kg of empty bag. It is because of the fact … Read more
Difference Between Validation and Calibration
Validation is documented evidence that gives assurance that a process will consistently produce a product with pre-defined specifications and quality. Validation is documented proof that a process, procedure, or activity will produce the same results in testing and production. Why Validation? Validation is the requirement of the FDA and other regulatory bodies that demand that … Read more